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An ancient neurotrophin receptor code; a single Runx/Cbfβ complex determines somatosensory neuron fate specification in zebrafish

In terrestrial vertebrates such as birds and mammals, neurotrophin receptor expression is considered fundamental for the specification of distinct somatosensory neuron types where TrkA, TrkB and TrkC specify nociceptors, mechanoceptors and proprioceptors/mechanoceptors, respectively. In turn, Runx t...

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Detalles Bibliográficos
Autores principales: Gau, Philia, Curtright, Andrew, Condon, Logan, Raible, David W., Dhaka, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533457/
https://www.ncbi.nlm.nih.gov/pubmed/28708822
http://dx.doi.org/10.1371/journal.pgen.1006884