CYP2D6 phenotypes are associated with adverse outcomes related to opioid medications

BACKGROUND: Variation in the CYP2D6 gene may affect response to opioids in both poor and ultrarapid metabolizers, but data demonstrating such associations have been mixed, and the impact of variants on toxicity-related symptoms (e.g., nausea) is unclear. Therefore, we examined the association betwee...

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Detalles Bibliográficos
Autores principales: St Sauver, Jennifer L, Olson, Janet E, Roger, Veronique L, Nicholson, Wayne T, Black, John L, Takahashi, Paul Y, Caraballo, Pedro J, Bell, Elizabeth J, Jacobson, Debra J, Larson, Nicholas B, Bielinski, Suzette J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533497/
https://www.ncbi.nlm.nih.gov/pubmed/28769582
http://dx.doi.org/10.2147/PGPM.S136341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533497/
https://www.ncbi.nlm.nih.gov/pubmed/28769582
http://dx.doi.org/10.2147/PGPM.S136341

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