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Two-step membrane binding by the bacterial SRP receptor enable efficient and accurate Co-translational protein targeting

The signal recognition particle (SRP) delivers ~30% of the proteome to the eukaryotic endoplasmic reticulum, or the bacterial plasma membrane. The precise mechanism by which the bacterial SRP receptor, FtsY, interacts with and is regulated at the target membrane remain unclear. Here, quantitative an...

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Detalles Bibliográficos
Autores principales: Hwang Fu, Yu-Hsien, Huang, William Y C, Shen, Kuang, Groves, Jay T, Miller, Thomas, Shan, Shu-ou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533587/
https://www.ncbi.nlm.nih.gov/pubmed/28753124
http://dx.doi.org/10.7554/eLife.25885