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Observed crowding effects on Mycobacterium tuberculosis 2-trans-enoyl-ACP (CoA) reductase enzyme activity are not due to excluded volume only

The cellular milieu is a complex and crowded aqueous solution. Macromolecular crowding effects are commonly studied in vitro using crowding agents. The aim of the present study was to evaluate the effects, if any, of macromolecular synthetic crowding agents on the apparent steady-state kinetic param...

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Detalles Bibliográficos
Autores principales: Rotta, Mariane, Timmers, Luis F. S. M., Sequeiros-Borja, Carlos, Bizarro, Cristiano V., de Souza, Osmar N., Santos, Diogenes S., Basso, Luiz A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533716/
https://www.ncbi.nlm.nih.gov/pubmed/28754992
http://dx.doi.org/10.1038/s41598-017-07266-w