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DMF-MALDI: droplet based microfluidic combined to MALDI-TOF for focused peptide detection

We present an automated droplet microfluidic system (DMF) to generate monitored nanoliter aqueous droplets in oil and their deposition on a commercial stainless steel plate for MALDI-TOF analysis of peptides or protein digests. We demonstrate that DMF-MALDI combination focuses the analyte on the MAL...

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Detalles Bibliográficos
Autores principales: Mesbah, Kiarach, Thai, Robert, Bregant, Sarah, Malloggi, Florent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533719/
https://www.ncbi.nlm.nih.gov/pubmed/28754890
http://dx.doi.org/10.1038/s41598-017-06660-8