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KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance

Endometriosis is an inflammatory condition that is associated with progesterone resistance and cell proliferation, resulting in pain, infertility and pregnancy loss. We previously demonstrated phosphorylation of STAT3 in eutopic endometrium of infertile women with this disorder leading to over-expre...

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Detalles Bibliográficos
Autores principales: Yoo, Jung-Yoon, Kim, Tae Hoon, Fazleabas, Asgerally T., Palomino, Wilder A., Ahn, Soo Hyun, Tayade, Chandrakant, Schammel, David P., Young, Steven L., Jeong, Jae-Wook, Lessey, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533722/
https://www.ncbi.nlm.nih.gov/pubmed/28754906
http://dx.doi.org/10.1038/s41598-017-04577-w