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KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance
Endometriosis is an inflammatory condition that is associated with progesterone resistance and cell proliferation, resulting in pain, infertility and pregnancy loss. We previously demonstrated phosphorylation of STAT3 in eutopic endometrium of infertile women with this disorder leading to over-expre...
Autores principales: | Yoo, Jung-Yoon, Kim, Tae Hoon, Fazleabas, Asgerally T., Palomino, Wilder A., Ahn, Soo Hyun, Tayade, Chandrakant, Schammel, David P., Young, Steven L., Jeong, Jae-Wook, Lessey, Bruce A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533722/ https://www.ncbi.nlm.nih.gov/pubmed/28754906 http://dx.doi.org/10.1038/s41598-017-04577-w |
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