DDR2 controls the epithelial-mesenchymal-transition-related gene expression via c-Myb acetylation upon matrix stiffening

Increasing matrix stiffness caused by the extracellular matrix (ECM) deposition surrounding cancer cells is accompanied by epithelial–mesenchymal transition (EMT). Here, we show that expression levels of EMT marker genes along with discoidin domain receptor 2 (DDR2) can increase upon matrix stiffeni...

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Detalles Bibliográficos
Autores principales: Kim, Daehwan, You, Eunae, Jeong, Jangho, Ko, Panseon, Kim, Jung-Woong, Rhee, Sangmyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533734/
https://www.ncbi.nlm.nih.gov/pubmed/28754957
http://dx.doi.org/10.1038/s41598-017-07126-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533734/
https://www.ncbi.nlm.nih.gov/pubmed/28754957
http://dx.doi.org/10.1038/s41598-017-07126-7

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