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DDR2 controls the epithelial-mesenchymal-transition-related gene expression via c-Myb acetylation upon matrix stiffening
Increasing matrix stiffness caused by the extracellular matrix (ECM) deposition surrounding cancer cells is accompanied by epithelial–mesenchymal transition (EMT). Here, we show that expression levels of EMT marker genes along with discoidin domain receptor 2 (DDR2) can increase upon matrix stiffeni...
Autores principales: | Kim, Daehwan, You, Eunae, Jeong, Jangho, Ko, Panseon, Kim, Jung-Woong, Rhee, Sangmyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533734/ https://www.ncbi.nlm.nih.gov/pubmed/28754957 http://dx.doi.org/10.1038/s41598-017-07126-7 |
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