Activation of TGF-β signaling induces cell death via the unfolded protein response in Fuchs endothelial corneal dystrophy

Fuchs endothelial corneal dystrophy (FECD) is a slowly progressive bilateral disease of corneal endothelium in which accumulation of extracellular matrix (ECM) and loss of corneal endothelial cells (CECs) are phenotypic features. The corneal endothelium maintains corneal transparency by regulating w...

Descripción completa

Detalles Bibliográficos
Autores principales: Okumura, Naoki, Hashimoto, Keisuke, Kitahara, Miu, Okuda, Hirokazu, Ueda, Emi, Watanabe, Kyoko, Nakahara, Makiko, Sato, Takahiko, Kinoshita, Shigeru, Tourtas, Theofilos, Schlötzer-Schrehardt, Ursula, Kruse, Friedrich, Koizumi, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533742/
https://www.ncbi.nlm.nih.gov/pubmed/28754918
http://dx.doi.org/10.1038/s41598-017-06924-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533742/
https://www.ncbi.nlm.nih.gov/pubmed/28754918
http://dx.doi.org/10.1038/s41598-017-06924-3

Ejemplares similares