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A cancer stem cell model as the point of origin of cancer-associated fibroblasts in tumor microenvironment
Cancer-associated fibroblasts (CAFs) are one of the most prominent cell types in the stromal compartment of the tumor microenvironment. CAFs support multiple aspects of cancer progression, including tumor initiation, invasion, and metastasis. The heterogeneous nature of the stromal microenvironment...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533745/ https://www.ncbi.nlm.nih.gov/pubmed/28754894 http://dx.doi.org/10.1038/s41598-017-07144-5 |