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Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness

Patients with severe alcoholic hepatitis (SAH) not responding to glucocorticoid therapy have higher mortality, though they do not differ in their baseline clinical characteristics and prognostic scores from those who respond to therapy. We hypothesized that the baseline hepatic gene expression diffe...

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Detalles Bibliográficos
Autores principales: Sharma, Shvetank, Maras, Jaswinder S., Das, Sukanta, Hussain, Shabir, Mishra, Ashwani K., Shasthry, Saggere M., Sharma, Chhagan B., Weiss, Emmanuel, Elkrief, Laure, Rautou, Pierre-Emmanuel, Gilgenkrantz, Hélène, Lotersztajn, Sophie, Paradis, Valérie, de la Grange, Pierre, Junot, Christophe, Moreau, Richard, Sarin, Shiv K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533759/
https://www.ncbi.nlm.nih.gov/pubmed/28754919
http://dx.doi.org/10.1038/s41598-017-07161-4