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Mass spectrometry-based determination of Kallikrein-related peptidase 7 (KLK7) cleavage preferences and subsite dependency

The cleavage preferences of Kallikrein-related peptidase 7 (KLK7) have previously been delineated using synthetic peptide libraries of fixed length, or single protein chains and have suggested that KLK7 exerts a chymotryptic-like cleavage preference. Due to the short length of the peptides utilised,...

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Detalles Bibliográficos
Autores principales: Silva, Lakmali Munasinghage, Stoll, Thomas, Kryza, Thomas, Stephens, Carson Ryan, Hastie, Marcus Lachlan, Irving-Rodgers, Helen Frances, Dong, Ying, Gorman, Jeffrey John, Clements, Judith Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533777/
https://www.ncbi.nlm.nih.gov/pubmed/28754951
http://dx.doi.org/10.1038/s41598-017-06680-4