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The Maintenance of Telomere Length in CD28+ T Cells During T Lymphocyte Stimulation

Telomerase activity is not readily detected in resting human T lymphocytes, however upon antigen presentation, telomerase is transiently upregulated. Presently, it is not known if telomerase activation is necessary for the proliferation of T cells or for the maintenance of telomere lengths. In this...

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Detalles Bibliográficos
Autores principales: Huang, Ejun (Elijah), Tedone, Enzo, O’Hara, Ryan, Cornelius, Crystal, Lai, Tsung-Po, Ludlow, Andrew, Wright, Woodring E., Shay, Jerry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533788/
https://www.ncbi.nlm.nih.gov/pubmed/28754961
http://dx.doi.org/10.1038/s41598-017-05174-7