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Mapping the chromatin landscape and Blimp1 transcriptional targets that regulate trophoblast differentiation

Trophoblast stem cells (TSCs) give rise to specialized cell types within the placenta. However, the regulatory mechanisms that guide trophoblast cell fate decisions during placenta development remain ill defined. Here we exploited ATAC-seq and transcriptional profiling strategies to describe dynamic...

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Detalles Bibliográficos
Autores principales: Nelson, Andrew C., Mould, Arne W., Bikoff, Elizabeth K., Robertson, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533796/
https://www.ncbi.nlm.nih.gov/pubmed/28754907
http://dx.doi.org/10.1038/s41598-017-06859-9