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Mapping the chromatin landscape and Blimp1 transcriptional targets that regulate trophoblast differentiation
Trophoblast stem cells (TSCs) give rise to specialized cell types within the placenta. However, the regulatory mechanisms that guide trophoblast cell fate decisions during placenta development remain ill defined. Here we exploited ATAC-seq and transcriptional profiling strategies to describe dynamic...
Autores principales: | Nelson, Andrew C., Mould, Arne W., Bikoff, Elizabeth K., Robertson, Elizabeth J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533796/ https://www.ncbi.nlm.nih.gov/pubmed/28754907 http://dx.doi.org/10.1038/s41598-017-06859-9 |
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