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PD-L1 expression in pancreatic ductal adenocarcinoma is a poor prognostic factor in patients with high CD8(+) tumor-infiltrating lymphocytes: highly sensitive detection using phosphor-integrated dot staining

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor prognosis. For the development of more effective immunotherapies, it is first necessary to elucidate the immunological escape mechanisms. In this study, we applied our recently developed highly sensitive immunostaining method...

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Detalles Bibliográficos
Autores principales: Yamaki, So, Yanagimoto, Hiroaki, Tsuta, Koji, Ryota, Hironori, Kon, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533855/
https://www.ncbi.nlm.nih.gov/pubmed/28314962
http://dx.doi.org/10.1007/s10147-017-1112-3