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Methods of probing the interactions between small molecules and disordered proteins
It is generally recognized that a large fraction of the human proteome is made up of proteins that remain disordered in their native states. Despite the fact that such proteins play key biological roles and are involved in many major human diseases, they still represent challenging targets for drug...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533867/ https://www.ncbi.nlm.nih.gov/pubmed/28631009 http://dx.doi.org/10.1007/s00018-017-2563-4 |