Late Maternal Folate Supplementation Rescues from Methyl Donor Deficiency-Associated Brain Defects by Restoring Let-7 and miR-34 Pathways

The micronutrients folate and vitamin B12 are essential for the proper development of the central nervous system, and their deficiency during pregnancy has been associated with a wide range of disorders. They act as methyl donors in the one-carbon metabolism which critically influences epigenetic me...

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Detalles Bibliográficos
Autores principales: Geoffroy, Andréa, Kerek, Racha, Pourié, Grégory, Helle, Déborah, Guéant, Jean-Louis, Daval, Jean-Luc, Bossenmeyer-Pourié, Carine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533871/
https://www.ncbi.nlm.nih.gov/pubmed/27534418
http://dx.doi.org/10.1007/s12035-016-0035-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533871/
https://www.ncbi.nlm.nih.gov/pubmed/27534418
http://dx.doi.org/10.1007/s12035-016-0035-8

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