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Design and implementation of a custom next generation sequencing panel for selected vitamin D associated genes

BACKGROUND: Biologically active vitamin D has an important regulatory role within the genome. It binds the vitamin D receptor (VDR) in order to control the expression of a wide range of genes as well as interacting with the epigenome to modify chromatin and methylation status. Vitamin D deficiency i...

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Detalles Bibliográficos
Autores principales: Benson, Katherine Angela, Chand, Sourabh, Maxwell, Alexander Peter, Smyth, Laura Jane, Kilner, Jill, Borrows, Richard, McKnight, Amy Jayne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534126/
https://www.ncbi.nlm.nih.gov/pubmed/28754147
http://dx.doi.org/10.1186/s13104-017-2664-z