Endothelial Notch signalling limits angiogenesis via control of artery formation

Angiogenic sprouting needs to be tightly controlled. It has been suggested that the Notch ligand dll4 expressed in leading tip cells restricts angiogenesis by activating Notch signalling in trailing stalk cells. Here, we show using live imaging in zebrafish that activation of Notch signalling is rat...

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Detalles Bibliográficos
Autores principales: Hasan, Sana S., Tsaryk, Roman, Lange, Martin, Wisniewski, Laura, Moore, John C., Lawson, Nathan D., Wojciechowska, Karolina, Schnittler, Hans, Siekmann, Arndt F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534340/
https://www.ncbi.nlm.nih.gov/pubmed/28714969
http://dx.doi.org/10.1038/ncb3574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534340/
https://www.ncbi.nlm.nih.gov/pubmed/28714969
http://dx.doi.org/10.1038/ncb3574

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