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Blockade of interleukin-6 receptor in the periphery promotes rapid and sustained antidepressant actions: a possible role of gut–microbiota–brain axis

Depression is a common, severe and chronic psychiatric disease. Although the currently available antidepressants have been used in the treatment of depression, their beneficial effects are limited. Accumulating evidence suggests that pro-inflammatory cytokines such as interleukin-6 (IL-6) have an im...

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Detalles Bibliográficos
Autores principales: Zhang, J-c, Yao, W, Dong, C, Yang, C, Ren, Q, Ma, M, Hashimoto, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534942/
https://www.ncbi.nlm.nih.gov/pubmed/28556833
http://dx.doi.org/10.1038/tp.2017.112