Incorrect dosage of IQSEC2, a known intellectual disability and epilepsy gene, disrupts dendritic spine morphogenesis

There is considerable genetic and phenotypic heterogeneity associated with intellectual disability (ID), specific learning disabilities, attention-deficit hyperactivity disorder, autism and epilepsy. The intelligence quotient (IQ) motif and SEC7 domain containing protein 2 gene (IQSEC2) is located o...

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Detalles Bibliográficos
Autores principales: Hinze, S J, Jackson, M R, Lie, S, Jolly, L, Field, M, Barry, S C, Harvey, R J, Shoubridge, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534949/
https://www.ncbi.nlm.nih.gov/pubmed/28463240
http://dx.doi.org/10.1038/tp.2017.81

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534949/
https://www.ncbi.nlm.nih.gov/pubmed/28463240
http://dx.doi.org/10.1038/tp.2017.81

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