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Serum kynurenic acid is reduced in affective psychosis

A subgroup of individuals with mood and psychotic disorders shows evidence of inflammation that leads to activation of the kynurenine pathway and the increased production of neuroactive kynurenine metabolites. Depression is hypothesized to be causally associated with an imbalance in the kynurenine p...

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Detalles Bibliográficos
Autores principales: Wurfel, B E, Drevets, W C, Bliss, S A, McMillin, J R, Suzuki, H, Ford, B N, Morris, H M, Teague, T K, Dantzer, R, Savitz, J B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534956/
https://www.ncbi.nlm.nih.gov/pubmed/28463241
http://dx.doi.org/10.1038/tp.2017.88