Metabolism of the Marine Phycotoxin PTX-2 and Its Effects on Hepatic Xenobiotic Metabolism: Activation of Nuclear Receptors and Modulation of the Phase I Cytochrome P450

PTX-2 is a marine biotoxin frequently found in shellfish that can lead to food intoxication in humans. Information regarding PTX-2 metabolism is scarce, and little is known of its effect on xenobiotic-metabolizing enzymes (XME) or its molecular pathways. The aim of this study was consequently to exa...

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Detalles Bibliográficos
Autores principales: Alarcan, Jimmy, Dubreil, Estelle, Huguet, Antoine, Hurtaud-Pessel, Dominique, Hessel-Pras, Stefanie, Lampen, Alfonso, Fessard, Valérie, Le Hegarat, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535159/
https://www.ncbi.nlm.nih.gov/pubmed/28678150
http://dx.doi.org/10.3390/toxins9070212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535159/
https://www.ncbi.nlm.nih.gov/pubmed/28678150
http://dx.doi.org/10.3390/toxins9070212

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