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Phage Display Analysis of Monoclonal Antibody Binding to Anthrax Toxin Lethal Factor

AVR1674 and AVR1675 are monoclonal antibodies (mAbs) that bind with high specificity to anthrax toxin lethal factor (LF) and lethal toxin (LTx). These mAbs have been used as pivotal reagents to develop anthrax toxin detection tests using mass spectrometry. The mAbs were demonstrated to bind LF with...

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Detalles Bibliográficos
Autores principales: Goldstein, Jason M., Lee, Joo, Tang, Xiaoling, Boyer, Anne E., Barr, John R., Bagarozzi, Dennis A., Quinn, Conrad P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535168/
http://dx.doi.org/10.3390/toxins9070221