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Differences in Genetic Background Contribute to Pseudomonas Exotoxin A-Induced Hepatotoxicity in Rats

Pseudomonas aeruginosa exotoxin A (PEA) causes severe hepatotoxicity in experimental animals and is useful in investigations of immune-mediated liver injury. However, strain differences in the sensitivity to PEA-induced hepatotoxicity in rats remains be elucidated. In this study, we determined the s...

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Detalles Bibliográficos
Autores principales: Chiu, Chien-Chao, Wang, Yu-Chih, Huang, Wen-Ching, Chen, Yi-Hsun, Hung, Shao-Wen, Huang, Yen-Te, Chuang, Hsiao-Li, Chang, Yi-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535171/
https://www.ncbi.nlm.nih.gov/pubmed/28714885
http://dx.doi.org/10.3390/toxins9070224