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Synthesis, Characterization, and Nanomedical Applications of Conjugates between Resorcinarene-Dendrimers and Ibuprofen

Ibuprofen has been reported to possess anticancer activity. In the present work, four ibuprofen conjugates of resorcinarene-Polyamidoamine PAMAM-dendrimers were synthesized with eight or 16 ibuprofen moieties. The ibuprofen was released from the dendrimers in a dependent manner. The drug-conjugated...

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Detalles Bibliográficos
Autores principales: Pedro-Hernández, Luis D., Martínez-Klimova, Elena, Cortez-Maya, Sandra, Mendoza-Cardozo, Sonia, Ramírez-Ápan, Teresa, Martínez-García, Marcos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535229/
https://www.ncbi.nlm.nih.gov/pubmed/28665319
http://dx.doi.org/10.3390/nano7070163