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GSK-3β suppresses HCC cell dissociation in vitro by upregulating epithelial junction proteins and inhibiting Wnt/β-catenin signaling pathway

Glycogen synthase kinase-3β (GSK-3β) is required in the expression of epithelial junction proteins. It was found downregulated in hepatocellular carcinoma (HCC) tissues. The purpose of this study was to investigate the role of GSK-3β in modulating the metastatic behaviors of human HCC cell lines in...

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Detalles Bibliográficos
Autores principales: Zhang, Jing-Hua, Jiao, Li-Yan, Li, Tie-Jun, Zhu, York Yuanyuan, Zhou, Jian-Wei, Tian, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535715/
https://www.ncbi.nlm.nih.gov/pubmed/28775779
http://dx.doi.org/10.7150/jca.18744