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Reverse Gyrase Functions in Genome Integrity Maintenance by Protecting DNA Breaks In Vivo

Reverse gyrase introduces positive supercoils to circular DNA and is implicated in genome stability maintenance in thermophiles. The extremely thermophilic crenarchaeon Sulfolobus encodes two reverse gyrase proteins, TopR1 (topoisomerase reverse gyrase 1) and TopR2, whose functions in thermophilic l...

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Detalles Bibliográficos
Autores principales: Han, Wenyuan, Feng, Xu, She, Qunxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535833/
https://www.ncbi.nlm.nih.gov/pubmed/28640207
http://dx.doi.org/10.3390/ijms18071340