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Reverse Gyrase Functions in Genome Integrity Maintenance by Protecting DNA Breaks In Vivo
Reverse gyrase introduces positive supercoils to circular DNA and is implicated in genome stability maintenance in thermophiles. The extremely thermophilic crenarchaeon Sulfolobus encodes two reverse gyrase proteins, TopR1 (topoisomerase reverse gyrase 1) and TopR2, whose functions in thermophilic l...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535833/ https://www.ncbi.nlm.nih.gov/pubmed/28640207 http://dx.doi.org/10.3390/ijms18071340 |