Novel Thiazolo[5,4-b]phenothiazine Derivatives: Synthesis, Structural Characterization, and In Vitro Evaluation of Antiproliferative Activity against Human Leukaemia

The molecular frame of the reported series of new polyheterocyclic compounds was intended to combine the potent phenothiazine and benzothiazole pharmacophoric units. The synthetic strategy applied was based on oxidative cyclization of N-(phenothiazin-3-yl)-thioamides and it was validated by the prep...

Descripción completa

Detalles Bibliográficos
Autores principales: Brem, Balazs, Gal, Emese, Găină, Luiza, Silaghi-Dumitrescu, Luminiţa, Fischer-Fodor, Eva, Tomuleasa, Ciprian Ionuţ, Grozav, Adriana, Zaharia, Valentin, Filip, Lorena, Cristea, Castelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535858/
https://www.ncbi.nlm.nih.gov/pubmed/28672876
http://dx.doi.org/10.3390/ijms18071365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535858/
https://www.ncbi.nlm.nih.gov/pubmed/28672876
http://dx.doi.org/10.3390/ijms18071365

Ejemplares similares