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Novel Thiazolo[5,4-b]phenothiazine Derivatives: Synthesis, Structural Characterization, and In Vitro Evaluation of Antiproliferative Activity against Human Leukaemia
The molecular frame of the reported series of new polyheterocyclic compounds was intended to combine the potent phenothiazine and benzothiazole pharmacophoric units. The synthetic strategy applied was based on oxidative cyclization of N-(phenothiazin-3-yl)-thioamides and it was validated by the prep...
Autores principales: | Brem, Balazs, Gal, Emese, Găină, Luiza, Silaghi-Dumitrescu, Luminiţa, Fischer-Fodor, Eva, Tomuleasa, Ciprian Ionuţ, Grozav, Adriana, Zaharia, Valentin, Filip, Lorena, Cristea, Castelia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535858/ https://www.ncbi.nlm.nih.gov/pubmed/28672876 http://dx.doi.org/10.3390/ijms18071365 |
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