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Profiling the Extended Cleavage Specificity of the House Dust Mite Protease Allergens Der p 1, Der p 3 and Der p 6 for the Prediction of New Cell Surface Protein Substrates

House dust mite (HDM) protease allergens, through cleavages of critical surface proteins, drastically influence the initiation of the Th2 type immune responses. However, few human protein substrates for HDM proteases have been identified so far, mainly by applying time-consuming target-specific indi...

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Detalles Bibliográficos
Autores principales: Jacquet, Alain, Campisi, Vincenzo, Szpakowska, Martyna, Dumez, Marie-Eve, Galleni, Moreno, Chevigné, Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535866/
https://www.ncbi.nlm.nih.gov/pubmed/28654001
http://dx.doi.org/10.3390/ijms18071373