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The Impact of Melatonin on Colon Cancer Cells’ Resistance to Doxorubicin in an In Vitro Study

Multi-drug resistance (MDR) is the main cause of low effectiveness of cancer chemotherapy. P-glycoprotein (P-gp) is one of the main factors determining MDR. Some studies indicate the potential role of melatonin (MLT) in MDR. In this study, we examined the effect of MLT on colon cancer cell’s resista...

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Detalles Bibliográficos
Autores principales: Fic, Magdalena, Gomulkiewicz, Agnieszka, Grzegrzolka, Jedrzej, Podhorska-Okolow, Marzenna, Zabel, Maciej, Dziegiel, Piotr, Jablonska, Karolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535889/
https://www.ncbi.nlm.nih.gov/pubmed/28788434
http://dx.doi.org/10.3390/ijms18071396