Cargando…

Histone Deacetylase Inhibitors as Anticancer Drugs

Carcinogenesis cannot be explained only by genetic alterations, but also involves epigenetic processes. Modification of histones by acetylation plays a key role in epigenetic regulation of gene expression and is controlled by the balance between histone deacetylases (HDAC) and histone acetyltransfer...

Descripción completa

Detalles Bibliográficos
Autores principales: Eckschlager, Tomas, Plch, Johana, Stiborova, Marie, Hrabeta, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535906/
https://www.ncbi.nlm.nih.gov/pubmed/28671573
http://dx.doi.org/10.3390/ijms18071414