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Quantitative Evaluation of Drug Resistance Profile of Cells Expressing Wild-Type or Genetic Polymorphic Variants of the Human ABC Transporter ABCC4

Broad-spectrum resistance in cancer cells is often caused by the overexpression of ABC transporters; which varies across individuals because of genetic single-nucleotide polymorphisms (SNPs). In the present study; we focused on human ABCC4 and established cells expressing the wild-type (WT) or SNP v...

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Detalles Bibliográficos
Autores principales: Tsukamoto, Megumi, Sato, Shiori, Satake, Kazuhiro, Miyake, Mizuki, Nakagawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535926/
https://www.ncbi.nlm.nih.gov/pubmed/28677646
http://dx.doi.org/10.3390/ijms18071435