Semi-Quantitative Mass Spectrometry in AML Cells Identifies New Non-Genomic Targets of the EZH2 Methyltransferase

Alterations to the gene encoding the EZH2 (KMT6A) methyltransferase, including both gain-of-function and loss-of-function, have been linked to a variety of haematological malignancies and solid tumours, suggesting a complex, context-dependent role of this methyltransferase. The successful implementa...

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Detalles Bibliográficos
Autores principales: Sbirkov, Yordan, Kwok, Colin, Bhamra, Amandeep, Thompson, Andrew J., Gil, Veronica, Zelent, Arthur, Petrie, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535931/
https://www.ncbi.nlm.nih.gov/pubmed/28678185
http://dx.doi.org/10.3390/ijms18071440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535931/
https://www.ncbi.nlm.nih.gov/pubmed/28678185
http://dx.doi.org/10.3390/ijms18071440

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