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Semi-Quantitative Mass Spectrometry in AML Cells Identifies New Non-Genomic Targets of the EZH2 Methyltransferase
Alterations to the gene encoding the EZH2 (KMT6A) methyltransferase, including both gain-of-function and loss-of-function, have been linked to a variety of haematological malignancies and solid tumours, suggesting a complex, context-dependent role of this methyltransferase. The successful implementa...
Autores principales: | Sbirkov, Yordan, Kwok, Colin, Bhamra, Amandeep, Thompson, Andrew J., Gil, Veronica, Zelent, Arthur, Petrie, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535931/ https://www.ncbi.nlm.nih.gov/pubmed/28678185 http://dx.doi.org/10.3390/ijms18071440 |
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