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Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells

Disturbances in histone acetyltransferases (HATs) are common in cancers. In urothelial carcinoma (UC), p300 and CBP are often mutated, whereas the GNAT family HATs GCN5 and PCAF (General Control Nonderepressible 5, p300/CBP-Associated Factor) are often upregulated. Here, we explored the effects of s...

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Detalles Bibliográficos
Autores principales: Koutsogiannouli, Evangelia A., Wagner, Nicholas, Hader, Christiane, Pinkerneil, Maria, Hoffmann, Michèle J., Schulz, Wolfgang A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535940/
https://www.ncbi.nlm.nih.gov/pubmed/28678170
http://dx.doi.org/10.3390/ijms18071449