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Chromatin Dynamics in Genome Stability: Roles in Suppressing Endogenous DNA Damage and Facilitating DNA Repair

Genomic DNA is compacted into chromatin through packaging with histone and non-histone proteins. Importantly, DNA accessibility is dynamically regulated to ensure genome stability. This is exemplified in the response to DNA damage where chromatin relaxation near genomic lesions serves to promote acc...

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Detalles Bibliográficos
Autores principales: Nair, Nidhi, Shoaib, Muhammad, Sørensen, Claus Storgaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535976/
https://www.ncbi.nlm.nih.gov/pubmed/28698521
http://dx.doi.org/10.3390/ijms18071486