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Rapamycin Maintains the Chondrocytic Phenotype and Interferes with Inflammatory Cytokine Induced Processes

Osteoarthritis (OA) is hallmarked by a progressive degradation of articular cartilage. Besides risk factors including trauma, obesity or genetic predisposition, inflammation has a major impact on the development of this chronic disease. During the course of inflammation, cytokines such as tumor necr...

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Detalles Bibliográficos
Autores principales: De Luna-Preitschopf, Andrea, Zwickl, Hannes, Nehrer, Stefan, Hengstschläger, Markus, Mikula, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535984/
https://www.ncbi.nlm.nih.gov/pubmed/28696356
http://dx.doi.org/10.3390/ijms18071494