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Licochalcone A Prevents Platelet Activation and Thrombus Formation through the Inhibition of PLCγ2-PKC, Akt, and MAPK Pathways

Platelet activation is involved in cardiovascular diseases, such as atherosclerosis and ischemic stroke. Licochalcone A (LA), an active ingredient of licorice, exhibits multiple biological activities such as anti-oxidation and anti-inflammation. However, its role in platelet activation remains uncle...

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Detalles Bibliográficos
Autores principales: Lien, Li-Ming, Lin, Kuan-Hung, Huang, Li-Ting, Tseng, Mei-Fang, Chiu, Hou-Chang, Chen, Ray-Jade, Lu, Wan-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535990/
https://www.ncbi.nlm.nih.gov/pubmed/28704925
http://dx.doi.org/10.3390/ijms18071500