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Programmed Cell Death 1 (PD-1) and Cytotoxic T Lymphocyte-Associated Antigen 4 (CTLA-4) in Viral Hepatitis

Virus-specific cluster of differentiation 8 (CD8+) cytotoxic T cells (CTL) recognize viral antigens presented on major histocompatibility complex (MHC) class I chains on infected hepatocytes, with help from CD4+ T cells. However, this CTL response is frequently weak or undetectable in patients with...

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Detalles Bibliográficos
Autores principales: Cho, Hyosun, Kang, Hyojeung, Lee, Hwan Hee, Kim, Chang Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536007/
https://www.ncbi.nlm.nih.gov/pubmed/28703774
http://dx.doi.org/10.3390/ijms18071517