BRD9 Inhibition, Alone or in Combination with Cytostatic Compounds as a Therapeutic Approach in Rhabdoid Tumors

Rhabdoid tumors (RT) are malignant neoplasms of early childhood. Despite intensive therapy, survival is poor and new treatment approaches are required. The only recurrent mutations in these tumors affect SMARCB1 and less commonly SMARCA4, both subunits of the chromatin remodeling complex SWItch/Sucr...

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Detalles Bibliográficos
Autores principales: Krämer, Katja F., Moreno, Natalia, Frühwald, Michael C., Kerl, Kornelius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536025/
https://www.ncbi.nlm.nih.gov/pubmed/28714904
http://dx.doi.org/10.3390/ijms18071537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536025/
https://www.ncbi.nlm.nih.gov/pubmed/28714904
http://dx.doi.org/10.3390/ijms18071537

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