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Prediction of Protein Hotspots from Whole Protein Sequences by a Random Projection Ensemble System
Hotspot residues are important in the determination of protein-protein interactions, and they always perform specific functions in biological processes. The determination of hotspot residues is by the commonly-used method of alanine scanning mutagenesis experiments, which is always costly and time c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536031/ https://www.ncbi.nlm.nih.gov/pubmed/28718782 http://dx.doi.org/10.3390/ijms18071543 |