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TGF-β-Dependent Growth Arrest and Cell Migration in Benign and Malignant Breast Epithelial Cells Are Antagonistically Controlled by Rac1 and Rac1b

Despite improvements in diagnosis and treatment, breast cancer is still the most common cancer type among non-smoking females. TGF-β can inhibit breast cancer development by inducing cell cycle arrest in both, cancer cells and, as part of a senescence program in normal human mammary epithelial cells...

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Detalles Bibliográficos
Autores principales: Melzer, Catharina, von der Ohe, Juliane, Hass, Ralf, Ungefroren, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536062/
https://www.ncbi.nlm.nih.gov/pubmed/28726720
http://dx.doi.org/10.3390/ijms18071574