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Investigating the Influence of Magnesium Ions on p53–DNA Binding Using Atomic Force Microscopy
p53 is a tumor suppressor protein that plays a significant role in apoptosis and senescence, preserving genomic stability, and preventing oncogene expression. Metal ions, such as magnesium and zinc ions, have important influences on p53–DNA interactions for stabilizing the structure of the protein a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536072/ https://www.ncbi.nlm.nih.gov/pubmed/28754018 http://dx.doi.org/10.3390/ijms18071585 |