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Investigating the Influence of Magnesium Ions on p53–DNA Binding Using Atomic Force Microscopy

p53 is a tumor suppressor protein that plays a significant role in apoptosis and senescence, preserving genomic stability, and preventing oncogene expression. Metal ions, such as magnesium and zinc ions, have important influences on p53–DNA interactions for stabilizing the structure of the protein a...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Gao, Tianyong, Wang, Yanwei, Yang, Guangcan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536072/
https://www.ncbi.nlm.nih.gov/pubmed/28754018
http://dx.doi.org/10.3390/ijms18071585