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The Role of p16(INK4a) Pathway in Human Epidermal Stem Cell Self-Renewal, Aging and Cancer

The epidermis is a self-renewing tissue. The balance between proliferation and differentiation processes is tightly regulated to ensure the maintenance of the stem cell (SC) population in the epidermis during life. Aging and cancer may be considered related endpoints of accumulating damages within e...

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Detalles Bibliográficos
Autores principales: D’Arcangelo, Daniela, Tinaburri, Lavinia, Dellambra, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536078/
https://www.ncbi.nlm.nih.gov/pubmed/28737694
http://dx.doi.org/10.3390/ijms18071591